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Therapeutic Areas:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Brukinsa
Zanubrutinib
2019-11-14
2034-2043
Mantle-cell lymphoma
,
Waldenstrom macroglobulinemia
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Zanubrutinib
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
reactive arthritis
,
preleukemia
,
liver failure
,
hepatic insufficiency
,
myelomonocytic leukemia chronic
,
t-cell lymphoma
,
neoplasms
,
recurrence
,
healthy volunteers/patients
,
thrombocytopenia
,
thrombocytopenic purpura idiopathic
,
hematologic neoplasms
,
hemolytic anemia autoimmune
,
syndrome
,
interdigitating dendritic cell sarcoma
,
paraproteinemias
,
therapeutics
,
anemia
,
hemolysis
,
hemolytic anemia
,
intraocular lymphoma
,
cardiovascular diseases
,
immune system diseases
,
blood protein disorders
,
lymphoproliferative disorders
,
plasma cell neoplasms
,
vascular diseases
,
neoplasms by histologic type
,
hemostatic disorders
,
immunoproliferative disorders
,
hemorrhagic disorders
,
castleman disease
,
lupus nephritis
,
nephritis
,
immunoglobulin g4-related disease
,
covid-19
,
prolymphocytic leukemia t-cell
,
central nervous system neoplasms
,
inflammation
,
aggression
,
antiphospholipid syndrome
,
neuromyelitis optica
,
polyneuropathies
,
monoclonal gammopathy of undetermined significance
,
maintenance chemotherapy
,
art therapy
,
lymphoma
,
b-cell lymphoma
,
large b-cell lymphoma diffuse
,
mantle-cell lymphoma
,
follicular lymphoma
,
b-cell lymphoma marginal zone
,
leukemia
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
hodgkin disease
,
membranous glomerulonephritis
,
b-cell chronic lymphocytic leukemia
,
waldenstrom macroglobulinemia
,
b-cell leukemia
,
lymphatic diseases
,
heart failure
,
atrial fibrillation
,
sudden death cardiac
,
heart arrest
,
supraventricular tachycardia
,
psoriasis
,
atopic dermatitis
,
eczema
,
hidradenitis suppurativa
,
pruritus
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
abscess
,
chronic urticaria
,
exanthema
,
urticaria
,
angioedema
,
photosensitivity disorders
,
amyloid plaque
,
erythema
Docusate
schizophrenia
,
hepatitis c
,
hepatitis
,
hepatitis a
,
viral hepatitis human
,
non-small-cell lung carcinoma
,
lung neoplasms
,
general anesthesia
,
hepatitis b
,
whooping cough
,
herpes zoster
,
mumps
,
tetanus
,
diphtheria
,
measles
,
haemophilus infections
,
chickenpox
,
poliomyelitis
,
rubella
,
migraine disorders
Histidine
macular edema
,
retinal vein occlusion
,
angioedema
Benzimidazole
healthy volunteers/patients
,
drug interactions
,
atopic dermatitis
,
dermatitis
,
eczema
,
multiple myeloma
,
plasma cell neoplasms
,
papillary thyroid cancer
,
autoimmune diseases
,
amyloidosis
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
Sitravatinib
non-small-cell lung carcinoma
,
lung neoplasms
,
adenocarcinoma
,
squamous cell carcinoma
,
squamous cell neoplasms
Ociperlimab
triple negative breast neoplasms
,
non-small-cell lung carcinoma
Gilvetmab
castration-resistant prostatic neoplasms
,
virus diseases
,
herpesviridae infections
,
prostatic neoplasms
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
,
neoplasms
,
leukemia
,
hematologic diseases
,
b-cell chronic lymphocytic leukemia
,
bone marrow diseases
,
carcinoma
,
small cell carcinoma
,
small cell lung carcinoma
,
neuroendocrine carcinoma
,
colorectal neoplasms
,
colonic neoplasms
,
colonic diseases
,
multiple myeloma
,
plasma cell neoplasms
Surufatinib
healthy volunteers/patients
,
renal insufficiency
,
liver diseases
,
hepatic insufficiency
,
neoplasms
,
small cell lung carcinoma
,
lung neoplasms
,
colorectal neoplasms
,
sarcoma
,
adenocarcinoma
,
cholangiocarcinoma
,
non-small-cell lung carcinoma
,
osteosarcoma
,
thyroid neoplasms
,
thyroid diseases
,
stomach neoplasms
,
ovarian neoplasms
,
chemoradiotherapy
,
head and neck neoplasms
,
breast neoplasms
,
pancreatic ductal carcinoma
,
hepatocellular carcinoma
,
ovarian epithelial carcinoma
,
squamous cell carcinoma
,
anaplastic thyroid carcinoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
digestive system neoplasms
,
peritoneal neoplasms
,
lymphoma
,
ewing sarcoma
,
rhabdomyosarcoma
,
male breast neoplasms
,
liver neoplasms
,
hematologic neoplasms
,
neoplasm metastasis
,
appendiceal neoplasms
,
triple negative breast neoplasms
,
carcinosarcoma
,
mullerian mixed tumor
,
ampulla of vater cancer
,
bile duct neoplasms
,
ductal carcinoma
,
immunotherapy
,
gallbladder neoplasms
,
islet cell adenoma
,
squamous cell carcinoma of head and neck
,
esophageal squamous cell carcinoma
,
carcinoma
,
pancreatic neoplasms
,
neuroendocrine tumors
,
biliary tract neoplasms
,
neuroendocrine carcinoma
,
salivary gland neoplasms
Aglatimagene besadenovec
renal cell carcinoma
,
colonic neoplasms
,
bone diseases
,
urethral neoplasms
,
transitional cell carcinoma
,
neoplasms
,
non-small-cell lung carcinoma
,
carcinoma
,
breast neoplasms
,
lung neoplasms
,
urinary bladder neoplasms
,
urologic neoplasms
,
melanoma
,
ovarian neoplasms
,
uterine cervical neoplasms
,
small cell lung carcinoma
,
small cell carcinoma
,
adenocarcinoma
,
triple negative breast neoplasms
,
neuroendocrine tumors
,
colorectal neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
squamous cell carcinoma
,
disease progression
,
squamous cell carcinoma of head and neck
,
recurrence
,
pancreatic neoplasms
,
endometrial neoplasms
,
stomach neoplasms
,
head and neck neoplasms
,
esophageal neoplasms
,
neoplasm metastasis
,
hyperplasia
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
prostatic hyperplasia
Vicriviroc
recurrence
,
carcinoma
,
lung neoplasms
,
small cell lung carcinoma
,
neuroendocrine tumors
,
neuroendocrine carcinoma
Doconexent
waldenstrom macroglobulinemia
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
philadelphia chromosome
,
lymphoid leukemia
,
head and neck neoplasms
,
myeloid leukemia acute
,
gata2 deficiency
,
plasma cell neoplasms
,
non-small-cell lung carcinoma
,
neoplasms
,
non-hodgkin lymphoma
,
glioblastoma
,
esophageal neoplasms
,
carcinoma
,
squamous cell carcinoma
,
squamous cell neoplasms
,
lung neoplasms
,
immunoglobulin light-chain amyloidosis
,
amyloidosis
,
adenocarcinoma of lung
,
bronchiolo-alveolar adenocarcinoma
,
prostatic neoplasms
,
neoplasm metastasis
,
recurrence
,
multiple myeloma
,
hodgkin disease
,
residual neoplasm
,
lymphoma
Lornoxicam
lymphoma
,
t-cell lymphoma
,
hematologic diseases
,
t-cell lymphoma peripheral
Pamiparib
head and neck neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
non-small-cell lung carcinoma
,
glioblastoma
,
prostatic neoplasms
,
recurrence
,
carcinoma
,
glioma
,
castration-resistant prostatic neoplasms
,
carcinosarcoma
,
mullerian mixed tumor
,
breast neoplasms
,
triple negative breast neoplasms
,
neoadjuvant therapy
,
lung neoplasms
,
biliary tract neoplasms
,
renal cell carcinoma
,
kidney neoplasms
,
leiomyomatosis
,
central nervous system neoplasms
,
nervous system neoplasms
,
stomach neoplasms
,
small cell lung carcinoma
,
salivary gland neoplasms
,
neoplasms
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
pancytopenia
,
hypertension
Aspartame
healthy volunteers/patients
,
colorectal neoplasms
,
chronic renal insufficiency
,
kidney diseases
,
sickle cell anemia
,
knee osteoarthritis
,
osteoarthritis
,
heart failure
,
lung neoplasms
,
ovarian neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
head and neck neoplasms
,
squamous cell carcinoma
,
squamous cell neoplasms
,
laryngeal neoplasms
,
opioid-related disorders
,
covid-19
,
coronavirus infections
,
carcinoma
,
neoplasms
,
urinary bladder neoplasms
,
brain neoplasms
,
glioma
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
body weight
,
cystic fibrosis
,
melanoma
,
biliary tract neoplasms
,
rare diseases
,
invasive hydatidiform mole
,
non-muscle invasive bladder neoplasms
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
mantle-cell lymphoma
,
b-cell lymphoma
,
b-cell leukemia
,
diabetes mellitus
,
chronic obstructive pulmonary disease
,
obesity
,
non-small-cell lung carcinoma
,
asthma
,
pulmonary eosinophilia
,
overweight
,
weight loss
,
hyperkalemia
,
endometrial neoplasms
,
borderline personality disorder
,
personality disorders
,
churg-strauss syndrome
,
eosinophilic granuloma
,
type 2 diabetes mellitus
,
breast neoplasms
,
fibrosis
,
inflammation
,
myocarditis
,
endomyocardial fibrosis
,
postoperative pain
,
depression
,
major depressive disorder
,
depressive disorder
Bevifimod
pharmacokinetics
,
inflammatory breast neoplasms
,
carcinoma
,
renal cell carcinoma
,
communicable diseases
,
pneumococcal infections
,
immune system diseases
,
triple negative breast neoplasms
,
diabetic foot
,
ulcer
,
foot ulcer
,
glioblastoma
,
gliosarcoma
,
astrocytoma
,
oligodendroglioma
,
small cell lung carcinoma
,
neoplasm metastasis
,
stomach neoplasms
,
esophageal neoplasms
,
hodgkin disease
,
adenocarcinoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
melanoma
,
bronchiolitis obliterans syndrome
,
meningitis
,
plasma cell neoplasms
,
squamous cell carcinoma of head and neck
,
ovarian epithelial carcinoma
,
human influenza
,
fallopian tube neoplasms
,
biliary tract neoplasms
,
prolymphocytic leukemia
,
pancreatic neoplasms
,
tuberculosis
,
hepatocellular carcinoma
,
liver neoplasms
,
head and neck neoplasms
,
pancreatic ductal carcinoma
,
induction chemotherapy
,
lung diseases
,
adenocarcinoma of lung
,
gestational diabetes
,
pregnancy in diabetics
,
coronary disease
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
brain neoplasms
,
mucopolysaccharidoses
,
mucopolysaccharidosis i
,
follicular lymphoma
,
hematopoietic stem cell transplantation
,
peripheral arterial disease
,
atherosclerosis
,
intermittent claudication
,
peripheral vascular diseases
,
mumps
,
measles
,
chickenpox
,
rubella
,
meningococcal meningitis
,
haemophilus infections
,
cutaneous malignant melanoma
,
esophageal squamous cell carcinoma
,
urinary bladder neoplasms
,
diarrhea
,
rectal neoplasms
,
congenital abnormalities
,
megakaryoblastic leukemia acute
,
monocytic leukemia acute
,
myelomonocytic leukemia acute
,
erythroblastic leukemia acute
,
hypersensitivity
,
peanut hypersensitivity
,
squamous cell carcinoma
,
squamous cell neoplasms
,
prolymphocytic leukemia t-cell
,
allergic rhinitis
,
rhinitis
,
acquired immunodeficiency syndrome
,
sezary syndrome
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
pulmonary alveolar proteinosis
,
preleukemia
,
t-cell lymphoma peripheral
,
laryngeal neoplasms
,
emphysema
,
alpha 1-antitrypsin deficiency
,
breast neoplasms
,
colorectal neoplasms
,
multiple myeloma
,
non-small-cell lung carcinoma
,
leukemia
,
lymphoma
,
myeloid leukemia acute
,
b-cell chronic lymphocytic leukemia
,
recurrence
,
lung neoplasms
,
myelodysplastic syndromes
,
diphtheria
,
ovarian neoplasms
,
whooping cough
,
tetanus
,
graft vs host disease
,
meningococcal infections
,
poliomyelitis
,
healthy volunteers/patients
,
hiv infections
,
hematologic neoplasms
,
hemophilia b
,
pneumococcal pneumonia
,
hepatitis
,
haemophilus influenzae type b
,
infections
,
hepatitis b
,
myeloid leukemia
,
thrombosis
,
venous thrombosis
,
rheumatoid arthritis
,
ascites
,
bcr-abl positive chronic myelogenous leukemia
,
aplastic anemia
,
thrombotic thrombocytopenic purpura
,
insulinoma
,
neuroendocrine tumors
,
carcinoid tumor
,
vipoma
,
paraneoplastic syndromes
,
islet cell carcinoma
,
islet cell adenoma
,
gastrinoma
,
glucagonoma
,
somatostatinoma
,
pulmonary embolism
,
embolism
,
motor activity
,
st elevation myocardial infarction
,
glucose intolerance
,
sclerosis
,
hematologic diseases
,
inborn genetic diseases
,
blood coagulation disorders
,
x-linked genetic diseases
,
hemorrhagic disorders
,
inherited blood coagulation disorders
,
coagulation protein disorders
,
fetal growth retardation
,
thromboembolism
,
noonan syndrome
,
bacterial meningitis
,
tonsillitis
,
myeloproliferative disorders
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
anemia
,
type 2 diabetes mellitus
,
type 1 diabetes mellitus
,
glycogen storage disease type ii
,
neoplasms
,
diabetes mellitus
,
prostatic neoplasms
,
non-hodgkin lymphoma
,
multiple sclerosis
,
hemophilia a
,
glycogen storage disease type iii
,
relapsing-remitting multiple sclerosis
,
covid-19
,
hyperglycemia
,
graft rejection
,
chronic kidney failure
,
insulin resistance
,
renal insufficiency
,
kidney transplantation
,
autologous transplantation
,
acute coronary syndrome
,
myocardial infarction
,
infarction
,
liver diseases
,
liver transplantation
,
psychology rejection
,
atrial fibrillation
,
pneumonia
,
hypertension
,
neutropenia
,
inflammation
,
heartburn
,
colitis
,
nasal polyps
,
asthma
,
inferior wall myocardial infarction
,
kidney diseases
,
coronary artery disease
,
immunosuppression therapy
,
fabry disease
,
anaphylaxis
,
glycogen storage disease
,
pregnancy
,
lymphoproliferative disorders
,
paraproteinemias
,
heart transplantation
,
reperfusion injury
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